U.S. flag

An official website of the United States government

Other Access

The information on this page (the dataset metadata) is also available in these formats:

JSON RDF

via the DKAN API

Manduca sexta Official Gene Set v2.0

Manduca sexta, known as the tobacco hornworm or Carolina sphinx moth, is a lepidopteran insect that is used extensively as a model system for research in insect biochemistry, physiology, neurobiology, development, and immunity. One important benefit of this species as an experimental model is its extremely large size, reaching more than 10 g in the larval stage. M. sexta larvae feed on solanaceous plants and thus must tolerate a substantial challenge from plant allelochemicals, including nicotine.

The official gene set is comprised of 15,451 protein-coding genes, of which 2498 were manually curated. Extensive RNA-seq data from many tissues and developmental stages were used to improve gene models and for insights into gene expression patterns. Genome wide synteny analysis indicated a high level of macrosynteny in the Lepidoptera. Annotation and analyses were carried out for gene families involved in a wide spectrum of biological processes, including apoptosis, vacuole sorting, growth and development, structures of exoskeleton, egg shells, and muscle, vision, chemosensation, ion channels, signal transduction, neuropeptide signaling, neurotransmitter synthesis and transport, nicotine tolerance, lipid metabolism, and immunity.

This dataset presents the Manduca sexta Official Gene Set (OGS) v2.0. It is predicted from genome assembly Msex_1.0 (GCA_000262585.1).

FieldValue
Tags
Modified
2019-11-04
Release Date
2019-10-02
Identifier
a12ced60-b5c3-4728-ad5b-7b7f5290c123
Publisher
Ag Data Commons
License
Contact Name
Kanost, Michael
Contact Email
Public Access Level
Public