epigenetics | Ag Data Commons

Genome-wide sequencing and comparative profiling of cattle sperm DNA methylome

National Center for Biotechnology Information

Using whole-genome bisulfite sequencing (WGBS), we profiled the DNA methylome of cattle sperms through comparison with three bovine somatic tissues (mammary grand, brain and blood).

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Histone modification dynamics at H3K27 in Pyricularia (Magnaporthe) oryzae

National Center for Biotechnology Information

Fungal plant pathogens use a diverse set of secreted proteins and small molecules, termed effectors, to suppress host immunity and promote colonization. Effectors are highly expressed in planta but remain transcriptionally repressed ex planta.

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Identifying improved sites for heterologous gene integration using ATAC-seq

National Center for Biotechnology Information

We analyzed the chromatin accessibility and nucleosome positioning by ATAC-seq of both null and transgene-expressing strains of Komagataella phaffii (Pichia pastoris) under different growth conditions.

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DNA Methylation data from frozen placental tissue

National Center for Biotechnology Information

Maternal obesity alters placental tissue function and morphology with a corresponding increase in local inflammation. We and others showed that placenta size, inflammation and fetal growth are regulated by maternal diet and obesity status.

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Comparative sperm methylome analysis provide insights into complex phenotypes and epigenome evolution

National Center for Biotechnology Information

Using whole-genome bisulfite sequencing (WGBS), we profiled 18 DNA methylomes of cattle sperms that were collected from 18 representative age-matched Holstein bulls with high reliable phenotypes on many complex traits, including sire-conception rate

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Acyrthosiphon pisum Whole Genome Bisulfite Sequencing

National Center for Biotechnology Information

Using whole genome bisulfite sequencing, we seek for differential methylation between bacteriocytes and other body cells as well as between specialized and universal host plants.

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Reduced representation bisulphite sequencing of ten bovine somatic tissues reveals DNA methylation patterns and their impacts on gene expression [RRBS-Seq]

National Center for Biotechnology Information

As a key epigenetic modification, DNA methylation is essential for normal development by regulating processes like gene expression, genomic imprinting, and suppression of repetitive elements.

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Genome-wide CpG island methylation and gene expression patterns in nuclear transfer donor cells in relation to cloning efficiency in swine

National Center for Biotechnology Information

The success of cloning by somatic cell nuclear transfer (SCNT) is unpredictable due in part to abnormal patterns of epigenetic marks in the donor cell genome which regulate gene expression.

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ChIP-seq of bovine cells (MDBK) to study butyrate-induced histone modification

National Center for Biotechnology Information

Utilizing next-generation sequencing technology, combined with ChIP (Chromatin Immunoprecipitation) technology to analyze histone modification (acetylation) induced by butyrate and to map the epigenomic landscape of normal histone H3, H4 Overall desi

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Data from: Functional annotation of the cattle genome through systematic discovery and characterization of chromatin states and butyrate-induced variations

The first complete global landscape of regulatory elements in cattle is presented and the dynamics of chromatin states in rumen epithelial cells induced by the rumen developmental regulator - butyrate- are explored.

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