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Data from: The influence of active video game play upon physical activity and screen-based activities in sedentary children

    Includes 24 hour recall data that children were instructed to fill-out describing the previous day’s activities, accelerometer data using an ActiGraph to assess usual physical and sedentary activity, participant demographic data, relative reinforcing value data showing how children rated how much they would want to perform both physical and sedentary activities. Also includes questionnaire data regarding exercise self-efficacy, motivation for physical activity, motivation for active video game, motivation for sedentary video games, and physical activity-related parenting behaviors.

    Data from: Skeletal Muscle Sexual Dimorphism in Mice

      File contains transcriptomics results for gastrocnemius (GA) and soleus (SOL) muscles from adult mice, previously fed a 45% (by energy) high fat diet for ~13 wk. The Supplemental Material also contains gene pathway analysis results (e.g., GO, HMDB), transcripts differentially expressed but with shared or disparate patterns in GA vs. SOL (Venn diagrams), and correlations between summed muscle weights vs. body weight or lean body mass.

      Human blood plasma oxylipins + endocannabinoids exercise patterns

        These data represent temporal changes in the concentrations of individual oxylipins (OxL) and endocannabinoids (eCB) in adult women during a sub-maximal aerobic exercise bout, and at recovery (20 min. post-cessation of exercise). Also depicted are statistical groupings of metabolites, as an Excel file.

        Data from: Exercise plasma metabolomics and xenometabolomics in obese, sedentary, insulin-resistant women: impact of a fitness and weight loss intervention

          Plasma metabolite patterns were determined during exercise and recovery in overnight-fasted sedentary, obese, insulin resistant women under controlled conditions of diet and physical activity to test the hypothesisis that improved fitness and insulin sensitivity following a ~14 wk training and weight loss intervention would lead to fixed workload plasma metabolomics signatures reflective of metabolic health and muscle metabolism. Supporting Materials include graphs of blood patterns of metabolites in adult women during a sub-maximal exercise bout and recovery period, and primary data in spreadsheet format on model performance, exercise and recovery, and correlation statistics for metabolites.

          Data from: Chondroitin sulfate disaccharides modified the structure and function of the murine gut microbiome under healthy and stressed conditions

            Chondroitin sulfate (CS) has been widely used for medical and nutraceutical purposes due to its roles in maintaining tissue structural integrity. We investigated if CS disaccharides may act as a bioactive compound and modulate gut microbial composition in mice. Our data show that CS disaccharides supplementation for 16 days significantly reduced blood LPS in the mice experiencing exhaustive exercise stress. CS disaccharides partially restored total fecal short-chain fatty acids from the level significantly repressed in mice under the stress. Our findings demonstrated that CS was likely butyrogenic and resulted in a significant increase in fecal butyrate concentration. CS disaccharides had a profound impact on gut microbial composition, affecting the abundance of 13.6% and 7.3% Operational Taxonomic Units in fecal microbial communities in healthy and stressed mice, respectively. CS disaccharides reduced the prevalence of inflammatory Proteobacteria. Together, our findings demonstrated that CS may ameliorate stress-induced intestinal inflammation. Furthermore, CS significantly increased intestinal *Bacteroides acidifaciens* population, indirectly exerting its immunomodulatory effect on the intestine. CS disaccharides had a significant impact on a broad range of biological pathways under stressed condition, such as ABC transporters, two-component systems, and carbohydrate metabolism. Our results will facilitate the development of CS as a bioactive nutraceutical.