This dataset contains research data compiled by the “Managing Water for Increased Resiliency of Drained Agricultural Landscapes” project a.k.a. Transforming Drainage (https://transformingdrainage.org). These data began in 1996 and include plot- and field-level measurements for 39 experiments across the Midwest and North Carolina. Practices studied include controlled drainage, drainage water recycling, and saturated buffers. In total, 219 variables are reported and span 207 site-years for tile drainage, 154 for nitrate-N load, 181 for water quality, 92 for water table, and 201 for crop yield.