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Regional epithelial cell diversity in the small intestine of pigs

    Single cell suspensions enriched for epithelial cells were obtained from duodenum, jejunum, and ileum of a 7.5-week-old pig and subjected to single-cell RNA sequencing (scRNA-seq). scRNA-seq was performed to provide transcriptomic profiles of epithelial cells, with 695 cells annotated into 6 cell types. Deeper interrogation of data revealed previously undescribed cells in porcine intestine, and region-specific gene expression profiles within specific cell subsets. Data herein includes a .h5seurat files of the epithelial cell subsets analyzed.

    Transcriptomic Analysis of Liver Indicates Novel Vaccine to Porcine Reproductive and Respiratory Virus Promotes Homeostasis in T-Cell and Inflammatory Immune Responses Compared to Commercial Vaccine in Pigs

    National Center for Biotechnology Information
      One of the largest impediments for commercial swine production is the presence of Porcine Reproductive and Respiratory Syndrome virus (PRRSV), a devastating RNA viral infection that is responsible for over $1 billion in loss in the U.S. annually.